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Rare serious Botox complications include allergic reactions manifesting as rash, itching, or breathing difficulties requiring immediate medical attention, systemic botulism symptoms from toxin spread beyond injection site (extremely rare with cosmetic doses), and vision problems from periocular injections affecting eye muscles

Mouse xenografts This study was reviewed and approved by the Fox Chase Cancer Center Institutional Animal Care and Use Committee (Protocol #16-10) and complies with ethical regulations for animal research

Furthermore, improving sensory attributes and optimizing formulation strategies are essential to enhance consumer acceptance and facilitate broader application in diverse food matrices

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