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Mostly, membrane integrity is dramatically disturbed resulting in lysis of the targeted microbes [11, 12]
This process is outlined below using the weighted 7-point check list
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By binding to GLP-1 receptors in the hypothalamus, they reduce appetite and promote satiety, leading to significant weight reduction in clinical trialswith newer agents achieving approximately 15% weight loss in obesity without diabetes (semaglutide) and up to 21% (tirzepatide), with somewhat lower reductions typically seen in patients with type 2 diabetes
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