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UV exposure induces the production of ROS, which subsequently activate the NF-B and MAPK signaling pathways, leading to increased transcription of pro-inflammatory cytokines (IL-1, TNF-, IL-6 and COX-2) and MMP-1, both of which contribute to inflammation and collagen degradation

60142-96-3 Appearance Solid Molecular Weight 171.24 Formula C 9 H 17 NO 2 Color White to off-white SMILES O=C(O)CC1(CN)CCCCC1 Shipping Room temperature in continental US

Phillyrin has also been shown to reduce glycocalyx shedding by inhibiting LPS-induced cathepsin L and ROS production