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Ipamorelin is noted for minimal cortisol effects compared to other secretagogues, but it still stimulates ghrelin-related pathways that can increase hunger

Although GLP-1 drugs like Ozempic may have some renal benefits, the studys authors stressed the need to monitor patients for adverse conditions like AIN and elevated serum creatinine levels

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Serum IGF-I levels alone are usually insufficient for diagnosing AGHD, so provocative tests such as the insulin tolerance test, glucagon stimulation test, or the combined GHRH-arginine test (where available) are needed (28)