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GIR: glucose infusion rate The following phase 2 data, comprising three clinical trials, demonstrated the potential to offer a simplified treatment option and compared different titration regimens with once-weekly insulin icodec for people with type 2 diabetes initiating insulin treatment, as well as investigated two different approaches to switch to once-weekly injection from other basal insulins

RESEARCH DESIGN AND METHODS We infused 12 diabetic patients and 12 nondiabetic control subjects with [2H]-glycine to measure GSH synthesis