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A small amount of the ingested vitamin B12 (one to two per cent) is absorbed by passive diffusion simply crossing the cell membranes without binding to anything (Temova Rakua et al., 2022)

24 weeks ~40 syringes Two injections per week from Week 9 onward

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DecramerMRutten-van MlkenMDekhuijzenPNTroostersTvan HerwaardenCPellegrinoRet alEffects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (bronchitis randomized on NAC cost-utility study, BRONCUS): a randomised placebo-controlled trial