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TIZI-035/001WO 322161-2568 [000199] Advanced molecular MRI using an iron-based inflammation and oxidative stress probe (Fe-PyC3A) measured via CNR revealed that nasal anti-CD3 antibody combined with low-dose (LD) semaglutide reduced liver inflammation by over 22-fold compared to LD alone (CNR=0.09 vs CNR=2.08)

Indeed, the authors showed that the TNBC LAR subtype, characterized by high expression of the androgen receptor, an increased ROS accumulation, and FA synthesis making LAR tumors highly sensitive to ferroptosis [22]

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