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Risk appears highest at the 2.4 mg dose
Contraindications Do Not Use If You Have a known hypersensitivity to any component of the formulation Have a history of kidney stones (high-dose vitamin C can increase oxalate and kidney stone risk) Have hereditary hemochromatosis or iron overload (vitamin C enhances iron absorption) Have glucose-6-phosphate dehydrogenase (G6PD) deficiency (high-dose IV vitamin C can cause hemolysis) Have severe kidney disease Are pregnant or breastfeeding (without specific medical supervision) Warnings and Precautions G6PD deficiency: High-dose vitamin C can cause red blood cell hemolysis in patients with G6PD deficiency
However, the specific mechanisms underlying these effects and their relevance to different subgroups of ADHD are still not well understood due to the relatively new and heterogeneous nature of research in this field
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