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It is an essential tool in detoxification and is a powerful immune booster
10.1007/s00018-009-0104-5 90 MuellerS.HilbertB.DueckershoffK.RoitschT.KrischkeM.MuellerM
When human knee-chondrocytes were transfected with lncRNA small nucleolar RNA host gene 1 (SNHG1) expression of pro-inflammatory cytokines and MMPs, including MMP-1, -3, and -9 decreased, and ECM degradation increased
In addition, ferroptosis is positively or negatively regulated by several transcription factors, including nuclear factor E2-related factor 2 (NRF2), activating transcription factor 3/4 (ATF3/4), Yes-associated protein 1 (YAP1), and hypoxia-inducible factor l (HIF1A) (28)
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