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The bold line indicates serially observed change in the diabetics while the dotted line shows is a projection that assumes that if diabetics were to continue on the therapy for longer time period the asymptotic values of HOMA2-IR may lie close to the non-diabetic numbers

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Common examples include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)