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Published preclinical and in vitro research has examined its interaction with extracellular matrix remodelling, broad gene-expression modulation, antioxidant and anti-inflammatory pathways, and copper-coordination chemistry in cultured fibroblasts and animal wound models

It accomplishes this primarily by inhibiting certain metabolic enzymes in the liver and intestinal wall that would otherwise break down beneficial compounds before they can be utilized by the body

The route of the nasal cavity not only avoids enzymatic degradation, a hazard of oral administration, but also offers rapid onset and consistent systemic delivery in scientific research settings

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