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The intersection of thyroid disorders and obesity management presents unique clinical considerations

120 A significant reduction in the rate of CoQ biosynthesis occurs during aging and age-associated diseases

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Oral antioxidants (e.g., vitamins C and E, lutein, and zeaxanthin) are widely used [7], but their low ocular bioavailability and poor tissue targeting often prevent therapeutic concentrations from being achieved at the disease site [8]