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Many adults in the United States are prescribed injectable medications like Ozempic and Trulicity for type 2 diabetes management

Regulatory standards for supplement manufacturing are less stringent than those for pharmaceuticals, which contributes to contamination and mislabeling

Additionally, "some herbal or 'natural' remedies for constipation, like aloe, cascara, or senna-based products are stimulant-based," says Hamilton, "meaning they work by causing the intestines to contract more forcefully." While these supplements can be effective for short-term relief, Hamilton warns that frequent use can lead to cramping, diarrhea, or dependence

For example, in a study by Mikhalkova et al