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Furthermore, MNs offer the potential for combination therapy and improved stability, making microneedle-based drug delivery an increasingly attractive approach in the fields of pharmaceuticals and healthcare [5]

In summary, the findings so far discussed point each other to the role of androgen/AR pathway impairment in skeletal muscle wasting, sarcopenia progression, obesity, insulin-resistance, inflammation and immuno-senescence

A scoping review published in 2025 in the journal Cureus noted an increasing number of reports of people losing hair while being treated with tirzepatide, dulaglutide and semaglutide

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