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Anti-inflammatory microglia contributes to stroke recovery by expressing anti-inflammatory cytokines, such as IL-10, IL-4, and some neurotrophic factors which prevent inflammation (100) and play important roles in tissue repair and wound healing ( All of these recovery processes lead to a stabilization of the permeability of the BBB, although several animal studies have shown increased permeability up to 1 (68) and further (189), suggesting that BBB remains open and permeable through this subacute stage

By stimulating insulin release and inhibiting glucagon, Tirzepatide helps stabilize blood sugar levels, reducing the risk of hyperglycemia, insulin resistance, and type 2 diabetes

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