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doi: 10.21608/BVMJ.2018.29426 93

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DJX-A-KM induces rapid and durable KRAS G12C degradation via the ubiquitinproteasome system To evaluate whether DJX-A-KM could degrade KRAS G12C across different mutant cell lines, we performed concentration-dependent assays in NCI-H358 and Mia PaCa-2 cells under the same conditions used for NCI-H23 cells