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Further studies are needed with adequate numbers of participants using highly accurate measures of CMF, such as positron emission tomography or cardiac magnetic resonance, to verify the hypothesis of GLP-1 and GLP-1 RAs affecting CMF

Providers may prescribe compounded drugs as needed to meet patient requirements or drug shortages

Figure 1 For example, after GLP-1RA stimulates the activation of AC (14), intracellular cAMP secretion increases, inhibits the signaling of the AKT and ERK1/2 pathways, and induces the apoptosis of tumor cells

Regular monitoring and supportive measures are essential to maintain the benefits achieved and promote long-term health and weight management