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Mann JFE, et al

Free Radic Res 2018;52:751-62

Obesity reduced the anti-cancer effects of the antidiabetic adiponectin receptor agonist AdipoRon in diet-induced obese mice with orthotopic pancreatic cancer through a mechanism involving IGF-1, IGF-1R, and ERK1/2 signaling ( However, despite such observations and the well-established epidemiological link between obesity and the severity of prostate cancer (11, 12), some reports raise questions about t the actual role of obesity in the progression of prostate cancer

Mecanismo de accin El Melanotan II ejerce su accin como agonista de los receptores de melanocortina acoplados a protena G