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In vivo and in vitro studies revealed that chlorogenic acid has anti-inflammatory effects by the activation of Sirt1 for Nrf2/NF-B regulation and reduce the brain neurons apoptosis (Zheng et al., 2022)

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Discussion In this review we have discussed the clinical, histopathologic and genetic features of various subtypes of acquired and congenital melanocytic nevi, as well as the new genetically defined concept of melanocytoma