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Cohen, 2023)

Oxidative stress and atrial fibrillation

This association with iron accumulation in chondrocytes is characterized by IL-1 upregulating TfR1 and DMT1 while downregulating FPN1, which exacerbates iron overload, disrupts ECM balance, and ultimately leads to cartilage damage ( In recent years, the roles of oxidative stress and mitochondrial dysfunction in the progression of OA have garnered significant attention (Suantawee et al., 2013