Select optionsPeptides Klotho (alphaKlothoLR) (20mcg) $499.00 $10,179.60Price range: $499.00 through $10,179.60 $249.50 $5,089.80Price range: $249.50 through $5,089.80 This product has multiple variants
Phase 1a: First-in-Human Single Ascending Dose Study (NCT02951806) Study Title: "Safety, Tolerability, and Pharmacokinetics of Single Doses of Cagrilintide in Healthy Subjects" Status: Completed Phase: Phase 1a Enrollment: 48 healthy volunteers Study Period: 2016-2017 Location: Single center (Denmark) Design: Randomized, double-blind, placebo-controlled, single ascending dose Dose Range: 0.03-10 mg SC Primary Endpoints: Safety, tolerability, PK parameters Population: Healthy male subjects, BMI 20-28 Key Results: Pharmacokinetics: Terminal half-life 5-7 days across dose range
It is the predominant intracellular non-protein thiol in mammalian tissues, present at concentrations typically ranging from 110 mM in the cytosol, with particularly high concentrations in the liver (up to 10 mM), which is the primary site of GSH synthesis and export
This can include individuals who are sensitive to medication side effects, have experienced difficulty tolerating standard GLP-1 dose escalation, or are looking for a lower-intensity approach under medical supervision
