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Activation of autophagy is regarded as a promising strategy for the prevention and treatment of metabolic diseases 65

Patients who may benefit most include: Adults with type 2 diabetes and hypertension This represents a common clinical scenario where metabolic and cardiovascular risk factors coexist

Secondary carnitine deficiency can be caused by increased losses, pharmacological therapy, a number of inherited metabolic disorders [38], poor diet or malabsorption of carnitine, from increased renal tubular loss of free carnitine (Fanconi syndrome), haemodialysis, peritoneal dialysis, or the increased excretion of acylcarnitines[39] with certain drugs

2025;12(30):e16709