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Possible side effects: Skin symptoms (acne as well as eczematous and urticarial drug reactions) and hypersensitivity symptoms (anaphylactic or anaphylactoid reactions) have been observed in very rare cases

L-carnitine with semaglutide is another popular combination, though its primary mechanism relates to fat oxidation rather than direct muscle preservation

41,42 In addition, lipid metabolism, inflammation, fibrosis, and cell death interact with each other, and the respective roles of GLP-1RA therein collectively comprise its therapeutic pathway in MASLD