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Semaglutide 2.4 mg was associated with mean weight losses of 14.9%-17.4% in individuals who are overweight or obese without type 2 diabetes in 68 weeks

However, the weight loss shown in all cases (severe and nonsevere) is maintained as long as the patient keeps taking the medicationits a chronic medication, not to be taken short-term. After the majority of weight is lost (usually within the initial months of taking semaglutide injections), progress generally slows progressively over time

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