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Over a mean follow-up period of 2.4 years, 0.2% of the GLP-1 receptor agonist cohort progressed to wet AMD compared with only 0.1% of control participants, resulting in an increased hazard for wet AMD of 2.21 for the GLP-1 RA cohort

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Its primary research application is as a pharmacological probe to selectively activate IGF1R in cell culture systems where IGFBP interference would otherwise complicate interpretation

[13] The size of the choroidal melanomas is the most important clinical feature in determining disease prognosis