To minimize the risk of hyperglycemia when initiating Insulin Glargine, U-300 monitor glucose daily, titrate Insulin Glargine, U-300 as described in this prescribing information, and adjust coadministered glucose-lowering therapies per standard of care [see Dosage and Administration (2.2, 2.3)]
The drug works primarily by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways
"With microdosing, you take a dose below the lowest approved dosage and may progress at a different pace than what's recommended." To help you wade through the noise and make an informed decision about microdosing GLP-1s, we asked Dr
In silico immunogenicity assessment for sequences containing unnatural amino acids: a method using existing in silico algorithm infrastructure and a vision for future enhancements