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As pues, el dao en el ADN y el potencial de fertilidad espermtico se han relacionado con la toxicidad provocada por el oxgeno y la accin de las especies reactivas de oxgeno (ROS, del ingls Reactive Oxygen Species)11

We observed that exposure to TGF- downregulated SC marker gene expression in c-MET-positive ZH-161 and ZH-305, but not in c-MET-negative T-269 cells (Fig.3 and Supplementary Fig

379,380 A phase I clinical trial in which pazopanib and vorinostat were combined to treat patients with p53-mutant tumors suggested that HDAC inhibitors can abolish the proangiogenic function of mutant p53

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