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Butyrate is directly used by the cell lining the gut for energy

This elevation in NAD+ activates SIRT1, a master regulator of metabolic pathways that promotes fat oxidation, enhances mitochondrial function, and improves insulin sensitivity

The PINK1/Parkin-mediated mitophagy is triggered when PINK1 is stabilized on the outer membrane of damaged mitochondria and recruites Parkin, an E3 ubiquitin ligase, followed by ubiquitination of mitochondrial proteins, which are then recognized by autophagy receptors [41]

Operators should establish a data logging system to track changes in headloss, TOC removal, turbidity, and UVT over time