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Some men reported improvements in erectile function and sexual health alongside the weight loss, which tracks with the hormonal improvements

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Favourable changes in cardiometabolic markers were also reported in the Phase 2 trial data, including reductions in: Systolic blood pressure Triglyceride levels Waist circumference (a proxy for visceral adiposity) However, these are surrogate markers and should not be interpreted as evidence of a reduction in major adverse cardiovascular events (MACE)

For a research laboratory, these studies offer benchmarks but do not constitute a rigorous level A evidence framework