glp-1 ra vs glp-1 GLP-1: Genetic Variants Related to Medications Frontiers | Glucagon-like peptide-1 receptor

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Laboratory studies have also shown that GLP-1 receptor activation can reduce reward-seeking behaviors in models exposed to drugs or highly palatable foods, supporting the biological plausibility of these observations (2 Trusted Source The glucagon-like peptide-1 analogue exendin-4 decreases the rewarding value of food and drug rewards

Since the blood-brain barrier prevents many dietary antioxidants from entering the brain, it largely relies on endogenous antioxidants such as Cu- and Zn-dependent superoxide dismutase (Cu, Zn SOD1)

No one predicted that GLP-1RAs would have this other function, though thats not an uncommon story with drugs