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In the case of powders, a chemical bond to tartaric acid - L-carnitine-L-tartrate - is used for stabilization

Recent analyses have raised questions about psychiatric side effects, particularly mood changes and anxiety. Patients with asthma may be at increased risk of respiratory complications, and nutrient deficiencies can occur with long-term therapy. Monitoring mental health and nutritional status should be part of any GLP-1 program

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This does not mean compounded semaglutide is unsafe, but it does mean the safety profile is dependent on the quality of the individual compounding pharmacy rather than the uniform manufacturing standards that govern FDA-approved drugs