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28 Fourati S , Guedj J , Chevaliez S , Nguyen THT , Roudot-Thoraval F , Ruiz I , et al

Symptoms of FM were previously attributed to dysfunction in central nociceptive sensory processing [15], which was explained by altered pain perception in FM patients, generalized hypersensitivity to unpleasant stimuli, altered cognitive functions, and sleep disturbances [16]

GLP-1 receptor agonists would not replace these evidence-based interventions, though they might be used concurrently to manage associated metabolic complications such as diabetes, if clinically appropriate and under specialist guidance

Adjustment Phase: A monthly medical update is conducted