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For the intervention, the rats in the PDA (3.6 mg/kg) and PDA@Pt (5 mg/kg) nanomedicine groups received intra-articular injections of the respective nanomedicines into the right ankle joint

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It is also worth noting that two of the supporting studies [38, 64] were rated as having a moderate risk of bias, which may influence the reliability of their findings

Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins