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Cardiovascular outcomes included composite endpoints as asserted in the Methods section and Figure 3 ascertains the reduction in those events, individual trials aligned with the cardioprotective benefits of SGLT inhibitor therapy

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In this light, the dissection of the complex association between dysmetabolism and PDAC, with a specific focus on stroma, and in particular on P4HA1 role, could help to unveil novel targets for prevention, early diagnosis and intervention aimed at reducing incidence and improving PDAC prognosis