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Eli Lilly, the compound developer, is running the Phase 3 TRIUMPH clinical trial program, and FDA approval is not expected before 2027 at the earliest

Jastreboff AM, Aronne LJ, Ahmad NN et al (2022) Tirzepatide once weekly for the treatment of obesity

Small meal examples help: a two-egg omelet with a quarter cup of spinach and one ounce of feta gives about 15 grams of protein and 5 grams of carbs, useful for sustained morning energy

Exenatide (shown on the right, PDB 7LLL), which was the first GLP-1 receptor agonist approved by the FDA, shares just over 50% sequence identity with GLP-1, but has a similar structure and is able to activate the GLP-1 receptor, while avoiding rapid proteolytic degradation