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Heterogeneity of drugs in MASH treatment
Having these conversations upfront prevents the common scenario where a patient starts tirzepatide, experiences symptoms of thyroid overmedication, and does not get labs drawn for months because nobody specified when to test
An AXR after around 6hrs since oral contrast* given can check to see evidence of ongoing obstruction versus resolution (if contrast passes distally to the obstruction, this is a good prognostic sign) *Gastrograffin (a common oral contrast medium used for these studies) may have therapeutic properties in resolving obstruction, due to its osmotic effect on bowel wall oedema, however evidence for this remains equivocal Patients who have not had any previous abdominal surgery would be less likely to have adhesional bowel obstruction, and in such cases conservative management would be less likely to succeed
Action and function of Akkermansia muciniphila in microbiome ecology, health and disease
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