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The IRO process typically takes 30 to 45 days for standard cases, or 72 hours for urgent cases involving active medical deterioration

Its ability to affect thousands of genes, induce collagen formation, contribute to tissue repair, and accelerate wound healing makes it a subject of intense interest in both anti-aging and regenerative studies

To gain further insight, a non-compartmental PK analysis was performed using gPKPDSim 74 , which revealed a 3.8-fold slower clearance rate (CL) and a 2.4-fold longer mean residence time (MRT) of QMP compared with WT albumin (Supplementary Table 4)

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