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Cell Rep Med 2022;3:100813.ArticlePubMedPMC 93

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Although much research has focused on mechanisms within the central nervous system to explain this pain suppression 8 , we hypothesize that additional mechanisms occurring in the peripheral nervous system are based on hormonal regulation during digestion

The neighborhood is home to the iconic Second City, a comedy club that has been a launching pad for numerous famous comedians and continues to offer top-notch sketch and improv shows